Clinical trial design and dissemination: comprehensive analysis of clinicaltrials.gov and PubMed data since 2005

Abstract

Clinicaltrials.gov is the world’s largest primary registry of clinical studies. For almost two decades now  it has been helping physicians, patients, and regulators identify relevant trials and collect evidence. It also offers a unique opportunity to explore, examine, and monitor the clinical research landscape.  In our recent research paper, we used the clinicaltrials.gov registry data to conduct a comprehensive large-scale analysis of registered clinical trials and investigate trends in their design and transparency.